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Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway
The insulin-like growth factor-1 receptor (IGF1R) has been identified as a potent anti-apoptotic, pro-survival tyrosine kinase-containing receptor. Overexpression of the IGF1R gene constitutes a typical feature of most human cancers. Consistent with these biological roles, cells expressing high leve...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817802/ https://ncbi.nlm.nih.gov/pubmed/29455671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0807-z |
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