Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model

Adult T-cell leukemia (ATL) is a malignant disease caused by human T-lymphotropic virus type 1. In aggressive ATL, the response to chemotherapy is extremely poor. We hypothesized that this poor response is due to the existence of chemotherapy-resistant cells, such as leukemic stem cells. Previously,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kuribayashi, Wakako, Takizawa, Kazuya, Sugata, Kenji, Kuramitsu, Madoka, Momose, Haruka, Sasaki, Eita, Hiradate, Yuki, Furuhata, Keiko, Asada, Yoshihisa, Iwama, Atsushi, Matsuoka, Masao, Mizukami, Takuo, Hamaguchi, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239456/
https://ncbi.nlm.nih.gov/pubmed/27340921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10210
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