Establishment of a New Quality Control and Vaccine Safety Test for Influenza Vaccines and Adjuvants Using Gene Expression Profiling

We have previously identified 17 biomarker genes which were upregulated by whole virion influenza vaccines, and reported that gene expression profiles of these biomarker genes had a good correlation with conventional animal safety tests checking body weight and leukocyte counts. In this study, we ha...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Momose, Haruka, Mizukami, Takuo, Kuramitsu, Madoka, Takizawa, Kazuya, Masumi, Atsuko, Araki, Kumiko, Furuhata, Keiko, Yamaguchi, Kazunari, Hamaguchi, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409070/
https://ncbi.nlm.nih.gov/pubmed/25909814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124392
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