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Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine

Safety evaluation of a human vaccine is critical for vaccine development and for preventing an unexpected adverse reaction in humans. Nonetheless, to date, very few systems have been described for preclinical studies of human adverse reactions in vivo. Previously, we have identified biomarker genes...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Sasaki, Eita, Momose, Haruka, Hiradate, Yuki, Furuhata, Keiko, Mizukami, Takuo, Hamaguchi, Isao
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995229/
https://ncbi.nlm.nih.gov/pubmed/29899819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25399
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