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Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine

Safety evaluation of a human vaccine is critical for vaccine development and for preventing an unexpected adverse reaction in humans. Nonetheless, to date, very few systems have been described for preclinical studies of human adverse reactions in vivo. Previously, we have identified biomarker genes...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sasaki, Eita, Momose, Haruka, Hiradate, Yuki, Furuhata, Keiko, Mizukami, Takuo, Hamaguchi, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995229/
https://ncbi.nlm.nih.gov/pubmed/29899819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25399
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