Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte

Epsins are a conserved family of endocytic adaptors essential for diverse biological events. However, its role in oocytes remains completely unknown. Here, we report that specific depletion of Epsin2 in mouse oocytes significantly disrupts meiotic progression. Confocal microscopy reveals that Epsin2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Ling, Han, Longsen, Zhang, Jiaqi, Liu, Xiaohui, Ma, Rujun, Hou, Xiaojing, Ge, Juan, Wang, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper: Pathology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239448/
https://ncbi.nlm.nih.gov/pubmed/27463009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10815
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