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Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes

Asymmetric meiotic divisions in mammalian oocytes rely on the eccentric positioning of the spindle and the remodeling of the overlying cortex, resulting in the formation of small polar bodies. The mechanism of this cortical polarization, exemplified by the formation of a thick F-actin cap, is poorly...

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Библиографические подробности
Главные авторы: Dehapiot, Benoit, Carrière, Virginie, Carroll, John, Halet, Guillaume
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690527/
https://ncbi.nlm.nih.gov/pubmed/23384564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.01.029
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