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Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes

Asymmetric meiotic divisions in mammalian oocytes rely on the eccentric positioning of the spindle and the remodeling of the overlying cortex, resulting in the formation of small polar bodies. The mechanism of this cortical polarization, exemplified by the formation of a thick F-actin cap, is poorly...

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Detalhes bibliográficos
Main Authors: Dehapiot, Benoit, Carrière, Virginie, Carroll, John, Halet, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690527/
https://ncbi.nlm.nih.gov/pubmed/23384564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.01.029
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