Activation of proinflammatory signaling by 4-hydroxynonenal-Src adducts in aged kidneys

In our previous study, reactive 4-hydroxy-2-nonenal (4-HNE) was shown to activate Src (a non-receptor tyrosine kinase) by forming an adduct on binding with a specific residue of Src, leading to the activation of proinflammatory signaling pathways in cultured cells. However, to date, the deleterious...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Jang, Eun Ji, Kim, Dae Hyun, Lee, Bonggi, Lee, Eun Kyeong, Chung, Ki Wung, Moon, Kyoung Mi, Kim, Min Jo, An, Hye Jin, Jeong, Ji Won, Kim, Ye Ra, Yu, Byung Pal, Chung, Hae Young
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper: Gerotarget (Focus on Aging)
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239442/
https://ncbi.nlm.nih.gov/pubmed/27472463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10854
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