The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

The prognosis of advanced hepatocellular carcinoma (HCC) is dismal. Novel molecular targets for diagnosis and therapy is urgently required. This study evaluated expression and functions of the protein arginine methyltransferase 5 (PRMT5) in HCC. Using HCC cell lines, the expression levels of PRMT5 m...

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Dades bibliogràfiques
Publicat a:Int J Oncol
Autors principals: Shimizu, Dai, Kanda, Mitsuro, Sugimoto, Hiroyuki, Shibata, Masahiro, Tanaka, Haruyoshi, Takami, Hideki, Iwata, Naoki, Hayashi, Masamichi, Tanaka, Chie, Kobayashi, Daisuke, Yamada, Suguru, Nakayama, Goro, Koike, Masahiko, Fujiwara, Michitaka, Fujii, Tsutomu, Kodera, Yasuhiro
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238779/
https://ncbi.nlm.nih.gov/pubmed/28101581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.3833
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