The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

The prognosis of advanced hepatocellular carcinoma (HCC) is dismal. Novel molecular targets for diagnosis and therapy is urgently required. This study evaluated expression and functions of the protein arginine methyltransferase 5 (PRMT5) in HCC. Using HCC cell lines, the expression levels of PRMT5 m...

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Gepubliceerd in:Int J Oncol
Hoofdauteurs: Shimizu, Dai, Kanda, Mitsuro, Sugimoto, Hiroyuki, Shibata, Masahiro, Tanaka, Haruyoshi, Takami, Hideki, Iwata, Naoki, Hayashi, Masamichi, Tanaka, Chie, Kobayashi, Daisuke, Yamada, Suguru, Nakayama, Goro, Koike, Masahiko, Fujiwara, Michitaka, Fujii, Tsutomu, Kodera, Yasuhiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238779/
https://ncbi.nlm.nih.gov/pubmed/28101581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.3833
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