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The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

The prognosis of advanced hepatocellular carcinoma (HCC) is dismal. Novel molecular targets for diagnosis and therapy is urgently required. This study evaluated expression and functions of the protein arginine methyltransferase 5 (PRMT5) in HCC. Using HCC cell lines, the expression levels of PRMT5 m...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Shimizu, Dai, Kanda, Mitsuro, Sugimoto, Hiroyuki, Shibata, Masahiro, Tanaka, Haruyoshi, Takami, Hideki, Iwata, Naoki, Hayashi, Masamichi, Tanaka, Chie, Kobayashi, Daisuke, Yamada, Suguru, Nakayama, Goro, Koike, Masahiko, Fujiwara, Michitaka, Fujii, Tsutomu, Kodera, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238779/
https://ncbi.nlm.nih.gov/pubmed/28101581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.3833
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