The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

The prognosis of advanced hepatocellular carcinoma (HCC) is dismal. Novel molecular targets for diagnosis and therapy is urgently required. This study evaluated expression and functions of the protein arginine methyltransferase 5 (PRMT5) in HCC. Using HCC cell lines, the expression levels of PRMT5 m...

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Vydáno v:Int J Oncol
Hlavní autoři: Shimizu, Dai, Kanda, Mitsuro, Sugimoto, Hiroyuki, Shibata, Masahiro, Tanaka, Haruyoshi, Takami, Hideki, Iwata, Naoki, Hayashi, Masamichi, Tanaka, Chie, Kobayashi, Daisuke, Yamada, Suguru, Nakayama, Goro, Koike, Masahiko, Fujiwara, Michitaka, Fujii, Tsutomu, Kodera, Yasuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238779/
https://ncbi.nlm.nih.gov/pubmed/28101581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.3833
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