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Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds

[Image: see text] The area of multitarget compounds, joining two pharmacophores within one molecule, is a vivid field of research in medicinal chemistry. Not only pharmacophoric elements are essential for the design and activity of such compounds, but the type and length of linkers used to connect t...

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Publicado en:ACS Med Chem Lett
Autores principales: Dyniewicz, Jolanta, Lipiński, Piotr F. J., Kosson, Piotr, Leśniak, Anna, Bochyńska-Czyż, Marta, Muchowska, Adriana, Tourwé, Dirk, Ballet, Steven, Misicka, Aleksandra, Lipkowski, Andrzej W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2016
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238479/
https://ncbi.nlm.nih.gov/pubmed/28105278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00381
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