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Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus

In the present contribution, we analyze the influence that C-terminal extension of short opioid peptide sequences by organic fragments has on receptor affinity, in vivo analgesic activity, and antimelanoma properties. The considered fragments were based on either N-acylhydrazone (NAH) or N′-acylhydr...

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Foilsithe in:Molecules
Main Authors: Dyniewicz, Jolanta, Lipiński, Piotr F. J., Kosson, Piotr, Bochyńska-Czyż, Marta, Matalińska, Joanna, Misicka, Aleksandra
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435865/
https://ncbi.nlm.nih.gov/pubmed/32731576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153429
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