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PK20, a new opioid-neurotensin hybrid peptide that exhibits central and peripheral antinociceptive effects

BACKGROUND: The clinical treatment of various types of pain relies upon the use of opioid analgesics. However most of them produce, in addition to the analgesic effect, several side effects such as the development of dependence and addiction as well as sedation, dysphoria, and constipation. One solu...

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Detalhes bibliográficos
Main Authors: Kleczkowska, Patrycja, Kosson, Piotr, Ballet, Steven, Van den Eynde, Isabelle, Tsuda, Yuko, Tourwé, Dirk, Lipkowski, Andrzej W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017538/
https://ncbi.nlm.nih.gov/pubmed/21134256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-86
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