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Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type

In most human sporadic prion diseases the phenotype is consistently associated with specific pairings of the genotype at codon 129 of the prion protein gene and conformational properties of the scrapie PrP (PrP(Sc)) grossly identified types 1 and 2. This association suggests that the 129 genotype fa...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Cracco, Laura, Notari, Silvio, Cali, Ignazio, Sy, Man-Sun, Chen, Shu G., Cohen, Mark L., Ghetti, Bernardino, Appleby, Brian S., Zou, Wen-Quan, Caughey, Byron, Safar, Jiri G., Gambetti, Pierluigi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238384/
https://ncbi.nlm.nih.gov/pubmed/28091514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38280
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