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Osteopontin regulates macrophage activation and osteoclast formation in hypertensive patients with vascular calcification

Vascular calcification (VC) is a highly regulated ectopic mineral deposition process involving immune cell infiltration in the vasculatures, which has been recognized to be promoted by hypertension. The matricellular glycoprotein osteopontin (OPN) is strongly induced in myeloid cells as a potential...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ge, Qian, Ruan, Cheng-Chao, Ma, Yu, Tang, Xiao-Feng, Wu, Qi-Hong, Wang, Ji-Guang, Zhu, Ding-Liang, Gao, Ping-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238370/
https://ncbi.nlm.nih.gov/pubmed/28091516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40253
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