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Osteopontin regulates macrophage activation and osteoclast formation in hypertensive patients with vascular calcification

Vascular calcification (VC) is a highly regulated ectopic mineral deposition process involving immune cell infiltration in the vasculatures, which has been recognized to be promoted by hypertension. The matricellular glycoprotein osteopontin (OPN) is strongly induced in myeloid cells as a potential...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Ge, Qian, Ruan, Cheng-Chao, Ma, Yu, Tang, Xiao-Feng, Wu, Qi-Hong, Wang, Ji-Guang, Zhu, Ding-Liang, Gao, Ping-Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238370/
https://ncbi.nlm.nih.gov/pubmed/28091516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40253
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