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Sequence-specific DNA double-strand breaks induced by triplex forming 125I labeled oligonucleotides.

A triplex-forming oligonucleotide (TFO) complementary to the polypurine-polypyrimidine region of the nef gene of the Human Immunodeficiency Virus (HIV) was labeled with 125I at the C5 position of a single deoxycytosine residue. Labeled TFO was incubated with a plasmid containing a fragment of the ne...

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Autori principali: Panyutin, I G, Neumann, R D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC523766/
https://ncbi.nlm.nih.gov/pubmed/7800489
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