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Molecular modeling and docking of small molecule inhibitors against NEK2

Aberrant expression of NEK2 (NIMA-related kinase 2) is indicated in a wide variety of human cancers. NEK2 is highly correlated to multi drug resistance by activating drug efflux activity. Identification of new small molecule inhibitors targeted against NEK2 therefore, facilitates to increase drug se...

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Publicat a:Bioinformation
Autors principals: Ramachandran, Balaji, Kesavan, Sabitha, Rajkumar, Thangarajan
Format: Artigo
Idioma:Inglês
Publicat: Biomedical Informatics 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237649/
https://ncbi.nlm.nih.gov/pubmed/28104962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630012062
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