Human and E.coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct.

Synthetic DNA substrates containing an acetylaminofluorene (AAF) adduct at each of the three guanine in the G1G2CG3CC sequence were constructed and tested as substrates for reconstituted E.coli (A)BC excinuclease and human excinuclease in HeLa cell-free extract (CFE). The (A)BC excinulcease repaired...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Mu, D, Bertrand-Burggraf, E, Huang, J C, Fuchs, R P, Sancar, A, Fuchs, B P
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1994
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7702657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.23.4869
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