Human and E.coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct.

Synthetic DNA substrates containing an acetylaminofluorene (AAF) adduct at each of the three guanine in the G1G2CG3CC sequence were constructed and tested as substrates for reconstituted E.coli (A)BC excinuclease and human excinuclease in HeLa cell-free extract (CFE). The (A)BC excinulcease repaired...

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Hlavní autoři: Mu, D, Bertrand-Burggraf, E, Huang, J C, Fuchs, R P, Sancar, A, Fuchs, B P
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC523749/
https://ncbi.nlm.nih.gov/pubmed/7702657
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