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Upregulation of NOXA by 10-Hydroxycamptothecin plays a key role in inducing fibroblasts apoptosis and reducing epidural fibrosis

The fibrosis that develops following laminectomy or discectomy often causes serious complications, and the proliferation of fibroblasts is thought to be the major cause of epidural fibrosis. 10-Hydroxycamptothecin (HCPT) has been proven to be efficient in preventing epidural fibrosis, but the exact...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Dai, Jihang, Sun, Yu, Yan, Lianqi, Wang, Jingcheng, Li, Xiaolei, He, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237371/
https://ncbi.nlm.nih.gov/pubmed/28097065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2858
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