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Cold denaturation and 2H2O stabilization of a staphylococcal nuclease mutant.

Cold denaturation is now recognized as a general property of proteins but has been observed only under destabilizing conditions, such as moderate denaturant concentration or low pH. By destabilizing the protein using site-directed mutagenesis, we have observed cold denaturation at pH 7.0 in the abse...

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Hlavní autoři: Antonino, L C, Kautz, R A, Nakano, T, Fox, R O, Fink, A L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC52373/
https://ncbi.nlm.nih.gov/pubmed/1652762
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