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Replication-dependent unhooking of DNA interstrand cross-links by the NEIL3 glycosylase
During eukaryotic DNA interstrand cross-link (ICL) repair, cross-links are resolved (“unhooked”) by nucleolytic incisions surrounding the lesion. In vertebrates, ICL repair is triggered when replication forks collide with the lesion, leading to FANCI-FANCD2-dependent unhooking and formation of a dou...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5237264/ https://ncbi.nlm.nih.gov/pubmed/27693351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.008 |
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