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Ribozyme mediated degradation of beta-amyloid peptide precursor mRNA in COS-7 cells.
Two sets of eucaryotic expression vectors encoding trans-acting hammerhead ribozymes and trans-acting hairpin ribozymes were constructed. In one set of vectors ribozyme RNA transcription was placed under the control of a mouse mammary tumor virus long terminal repeat (MMTV-LTR). In the other set rib...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1994
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523698/ https://ncbi.nlm.nih.gov/pubmed/8036167 |
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