Aged Human Stored Red Blood Cell Supernatant Inhibits Macrophage Phagocytosis in an HMGB1 Dependent Manner after Trauma in a Murine Model

Red blood cell transfusions in the setting of trauma is a double edged sword, as it is a necessary component for life-sustaining treatment in massive hemorrhagic shock, but also associated with increased risk for nosocomial infections and immune suppression. The mechanisms surrounding this immune su...

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Bibliografske podrobnosti
izdano v:Shock
Main Authors: Zettel, Kent R., Dyer, Mitchell, Raval, Jay S., Wu, Xubo, Klune, John R., Gutierrez, Andres, Triulzi, Darrell J., Billiar, Timothy R., Neal, Matthew D.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235959/
https://ncbi.nlm.nih.gov/pubmed/27488090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000716
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