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Hepatic stellate cells increase the immunosuppressive function of natural Foxp3(+) regulatory T cells via IDO-induced AhR activation

Immunosuppressive, naturally occurring CD4(+)CD25(+)forkhead box p3(+) (Foxp3(+)) regulatory T cells (nT(regs)) offer potential for the treatment of immune-mediated inflammatory disorders. However, potential instability of ex vivo-expanded nT(regs) following their adoptive transfer may be a signific...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Kumar, Sudhir, Wang, Jiang, Thomson, Angus W., Gandhi, Chandrashekhar R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235903/
https://ncbi.nlm.nih.gov/pubmed/27581538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0516-239R
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