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AhR-Mediated, Non-Genomic Modulation of IDO1 Function
The evolutionary process has conferred a dual – enzymatic and signaling – function on the ancestral metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1), which has long been known for converting the essential amino acid tryptophan (TRP) into neuroactive and immunoactive catabolites (kynurenines). I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197771/ https://ncbi.nlm.nih.gov/pubmed/25360135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00497 |
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