AhR-Mediated, Non-Genomic Modulation of IDO1 Function

The evolutionary process has conferred a dual – enzymatic and signaling – function on the ancestral metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1), which has long been known for converting the essential amino acid tryptophan (TRP) into neuroactive and immunoactive catabolites (kynurenines). I...

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Autores principales: Pallotta, Maria Teresa, Fallarino, Francesca, Matino, Davide, Macchiarulo, Antonio, Orabona, Ciriana
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197771/
https://ncbi.nlm.nih.gov/pubmed/25360135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00497
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