Mutational analysis of the DNA binding domain A of chromosomal protein HMG1.

We have mutated several residues of the first of the two HMG-boxes of mammalian HMG1. Some mutants cannot be produced in Escherichia coli, suggesting that the peptide fold is grossly disrupted. A few others can be produced efficiently and have normal DNA binding affinity and specificity; however, th...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Falciola, L, Murchie, A I, Lilley, D M, Bianchi, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1994
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.3.285
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