Mutational analysis of the DNA binding domain A of chromosomal protein HMG1.
We have mutated several residues of the first of the two HMG-boxes of mammalian HMG1. Some mutants cannot be produced in Escherichia coli, suggesting that the peptide fold is grossly disrupted. A few others can be produced efficiently and have normal DNA binding affinity and specificity; however, th...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
1994
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| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.3.285 |
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