NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, and thereby regulate many cellular processes, but t...

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Publicado en:eLife
Autores principales: Ewald, Collin Yvès, Hourihan, John M, Bland, Monet S, Obieglo, Carolin, Katic, Iskra, Moronetti Mazzeo, Lorenza E, Alcedo, Joy, Blackwell, T Keith, Hynes, Nancy E
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235354/
https://ncbi.nlm.nih.gov/pubmed/28085666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19493
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