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Targeted disruption of the orphan receptor Gpr151 does not alter pain-related behaviour despite a strong induction in dorsal root ganglion expression in a model of neuropathic pain

BACKGROUND: Gpr151 is an orphan GPCR whose function is unknown. The restricted pattern of neuronal expression in the habenula, dorsal horn of the spinal cord and dorsal root ganglion plus homology with the galanin family of receptors imply a role in nociception. RESULTS: Real-time quantitative RT-PC...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Neurosci
Asıl Yazarlar: Holmes, Fiona E., Kerr, Niall, Chen, Ying-Ju, Vanderplank, Penny, McArdle, Craig A., Wynick, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Academic Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235321/
https://ncbi.nlm.nih.gov/pubmed/27913310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.11.010
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