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Targeted disruption of the orphan receptor Gpr151 does not alter pain-related behaviour despite a strong induction in dorsal root ganglion expression in a model of neuropathic pain

BACKGROUND: Gpr151 is an orphan GPCR whose function is unknown. The restricted pattern of neuronal expression in the habenula, dorsal horn of the spinal cord and dorsal root ganglion plus homology with the galanin family of receptors imply a role in nociception. RESULTS: Real-time quantitative RT-PC...

詳細記述

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書誌詳細
出版年:Mol Cell Neurosci
主要な著者: Holmes, Fiona E., Kerr, Niall, Chen, Ying-Ju, Vanderplank, Penny, McArdle, Craig A., Wynick, David
フォーマット: Artigo
言語:Inglês
出版事項: Academic Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235321/
https://ncbi.nlm.nih.gov/pubmed/27913310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.11.010
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