Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle.
To investigate the role of kinase-mediated mechanisms in regulating mammalian cell proliferation, we determined the effects of the general protein kinase inhibitor staurosporine on the proliferation of a series of nontransformed and transformed cultured rodent and human cells. Levels of staurosporin...
Sparad:
| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphov: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
National Academy of Sciences
1991
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1652754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7580 |
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