Targeting pathogen metabolism without collateral damage to the host

The development of drugs that can inactivate disease-causing cells (e.g. cancer cells or parasites) without causing collateral damage to healthy or to host cells is complicated by the fact that many proteins are very similar between organisms. Nevertheless, due to subtle, quantitative differences be...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haanstra, Jurgen R., Gerding, Albert, Dolga, Amalia M., Sorgdrager, Freek J. H., Buist-Homan, Manon, du Toit, François, Faber, Klaas Nico, Holzhütter, Hermann-Georg, Szöör, Balázs, Matthews, Keith R., Snoep, Jacky L., Westerhoff, Hans V., Bakker, Barbara M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234033/
https://ncbi.nlm.nih.gov/pubmed/28084422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40406
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