Aging and SKN-1-dependent Loss of 20S Proteasome Adaptation to Oxidative Stress in C. elegans

Aging is marked by a collapse of protein homeostasis and deterioration of adaptive stress responses that often lead to disease. During aging, the induction of stress responses decline along with protein quality control. Here, we have shown that the ability to mount an adaptive response by pretreatme...

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Détails bibliographiques
Publié dans:J Gerontol A Biol Sci Med Sci
Auteurs principaux: Raynes, Rachel, Juarez, Crystal, Pomatto, Laura C. D., Sieburth, Derek, Davies, Kelvin J. A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233911/
https://ncbi.nlm.nih.gov/pubmed/27341854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw093
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