Wordt geladen...

The age- and sex-specific decline of the 20s proteasome and the Nrf2/CncC signal transduction pathway in adaption and resistance to oxidative stress in Drosophila melanogaster

Hallmarks of aging include loss of protein homeostasis and dysregulation of stress-adaptive pathways. Loss of adaptive homeostasis, increases accumulation of DNA, protein, and lipid damage. During acute stress, the Cnc-C (Drosophila Nrf2 orthologue) transcriptionally-regulated 20S proteasome degrade...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Aging (Albany NY)
Hoofdauteurs: Pomatto, Laura C.D., Wong, Sarah, Carney, Caroline, Shen, Brenda, Tower, John, Davies, Kelvin J. A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425120/
https://ncbi.nlm.nih.gov/pubmed/28373600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101218
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!