Distinct cytoprotective roles of pyruvate and ATP by glucose metabolism on epithelial necroptosis and crypt proliferation in ischaemic gut

KEY POINTS: Intestinal ischaemia causes epithelial death and crypt dysfunction, leading to barrier defects and gut bacteria‐derived septic complications. Enteral glucose protects against ischaemic injury; however, the roles played by glucose metabolites such as pyruvate and ATP on epithelial death a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Physiol
Päätekijät: Huang, Ching‐Ying, Kuo, Wei‐Ting, Huang, Chung‐Yen, Lee, Tsung‐Chun, Chen, Chin‐Tin, Peng, Wei‐Hao, Lu, Kuo‐Shyan, Yang, Chung‐Yi, Yu, Linda Chia‐Hui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Alimentary
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233659/
https://ncbi.nlm.nih.gov/pubmed/27121603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272208
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