Intracellular ATP Concentration Contributes to the Cytotoxic and Cytoprotective Effects of Adenosine

Extracellular adenosine (Ade) interacts with cells by two pathways: by activating cell surface receptors at nanomolar/micromolar concentrations; and by interfering with the homeostasis of the intracellular nucleotide pool at millimolar concentrations. Ade shows both cytotoxic and cytoprotective effe...

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Detalhes bibliográficos
Main Authors: Li, Shujue, Li, Xiaofen, Guo, Haiping, Liu, Shouting, Huang, Hongbiao, Liu, Ningning, Yang, Changshan, Tang, Ping, Liu, Jinbao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789704/
https://ncbi.nlm.nih.gov/pubmed/24098558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076731
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