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Effects on Rotavirus Cell Binding and Infection of Monomeric and Polymeric Peptides Containing α2β1 and αxβ2 Integrin Ligand Sequences
Integrin-using rotaviruses bind MA104 cell surface α2β1 integrin via the Asp-Gly-Glu (DGE) sequence in virus spike protein VP4 and interact with αxβ2 integrin during cell entry through outer capsid protein VP7. Infection is inhibited by the α2β1 ligand Asp-Gly-Glu-Ala (DGEA) and the αxβ2 ligand Gly-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523290/ https://ncbi.nlm.nih.gov/pubmed/15479820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11786-11797.2004 |
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