Integrin-Using Rotaviruses Bind α2β1 Integrin α2 I Domain via VP4 DGE Sequence and Recognize αXβ2 and αVβ3 by Using VP7 during Cell Entry

Integrins α2β1, αXβ2, and αVβ3 have been implicated in rotavirus cell attachment and entry. The virus spike protein VP4 contains the α2β1 ligand sequence DGE at amino acid positions 308 to 310, and the outer capsid protein VP7 contains the αXβ2 ligand sequence GPR. To determine the viral proteins an...

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Detalhes bibliográficos
Main Authors: Graham, Kate L., Halasz, Peter, Tan, Yan, Hewish, Marilyn J., Takada, Yoshikazu, Mackow, Erich R., Robinson, Martyn K., Coulson, Barbara S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224597/
https://ncbi.nlm.nih.gov/pubmed/12941907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9969-9978.2003
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