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Determinants of the Specificity of Rotavirus Interactions with the α2β1 Integrin

The human α2β1 integrin binds collagen and acts as a cellular receptor for rotaviruses and human echovirus 1. These ligands require the inserted (I) domain within the α2 subunit of α2β1 for binding. Previous studies have identified the binding sites for collagen and echovirus 1 in the α2 I domain. W...

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Bibliografiset tiedot
Päätekijät: Fleming, Fiona E., Graham, Kate L., Takada, Yoshikazu, Coulson, Barbara S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057834/
https://ncbi.nlm.nih.gov/pubmed/21138834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142992
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