PI3Kγ Deficient NOD-Mice Are Protected from Diabetes by Restoring the Balance of Regulatory to Effector-T-Cells

With a steady increase in its incidence and lack of curative treatment, type 1 diabetes (T1D) has emerged as a major health problem worldwide. To design novel effective therapies, there is a pressing need to identify regulatory targets controlling the balance of autoreactive to regulatory-T-cells (T...

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Udgivet i:PLoS One
Main Authors: Azzi, Jamil, Thueson, Lindsay, Moore, Robert, Abdoli, Rozita, Reijonen, Helena, Abdi, Reza
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5231340/
https://ncbi.nlm.nih.gov/pubmed/28081180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169695
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