TSC1 regulates the balance between effector and regulatory T cells

Mammalian target of rapamycin (mTOR) plays a crucial role in the control of T cell fate determination; however, the precise regulatory mechanism of the mTOR pathway is not fully understood. We found that T cell–specific deletion of the gene encoding tuberous sclerosis 1 (TSC1), an upstream negative...

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Bibliographische Detailangaben
Hauptverfasser: Park, Yoon, Jin, Hyung-Seung, Lopez, Justine, Elly, Chris, Kim, Gisen, Murai, Masako, Kronenberg, Mitchell, Liu, Yun-Cai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859395/
https://ncbi.nlm.nih.gov/pubmed/24270422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69751
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