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Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

Regulatory T cells (T(reg) cells) that express the transcription factor Foxp3 suppress the activity of other cells. Here we show that interleukin 10 (IL-10) produced by CD11b(+) myeloid cells in recombination-activating gene 1–deficient (Rag1(−/−)) recipient mice was needed to prevent the colitis in...

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Detalhes bibliográficos
Main Authors: Murai, Masako, Turovskaya, Olga, Kim, Gisen, Madan, Rajat, Karp, Christopher L, Cheroutre, Hilde, Kronenberg, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898179/
https://ncbi.nlm.nih.gov/pubmed/19783988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1791
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