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The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection

Controlled human malaria infection (CHMI) in healthy human volunteers is an important and powerful tool in clinical malaria vaccine development. However, power calculations are essential to obtain meaningful estimates of protective efficacy, while minimizing the risk of adverse events. To optimize p...

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Publicado en:PLoS Comput Biol
Autores principales: Coffeng, Luc E., Hermsen, Cornelus C., Sauerwein, Robert W., de Vlas, Sake J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5230743/
https://ncbi.nlm.nih.gov/pubmed/28081133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005255
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