HMGB1 promotes the secretion of multiple cytokines and potentiates the osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway

High mobility group box 1 (HMGB1) protein has been previously been detected in the inflammatory microenvironment of bone fractures. It is well known that HMGB1 acts as a chemoattractant to mesenchymal stem cells (MSCs). In the present study, the effects of HMGB1 on cytokine secretion from MSCs were...

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Publicado no:Exp Ther Med
Main Authors: Feng, Lin, Xue, Deting, Chen, Erman, Zhang, Wei, Gao, Xiang, Yu, Jiawei, Feng, Yadong, Pan, Zhijun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228376/
https://ncbi.nlm.nih.gov/pubmed/28105126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3857
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