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Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

Fracture nonunion and delayed union continue to pose challenges for orthopedic surgeons. In the present study, we combined HMGB1 gelatin sponges with MSC sheets to promote bone healing after surgical treatment of rat tibial fractures. The HMGB1 gelatin sponge scaffolds supported the expansion of mes...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Xue, Deting, Zhang, Wei, Chen, Erman, Gao, Xiang, Liu, Ling, Ye, Chenyi, Tan, Yanbin, Pan, Zhijun, Li, Hang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522052/
https://ncbi.nlm.nih.gov/pubmed/28431400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16887
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