Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

Fracture nonunion and delayed union continue to pose challenges for orthopedic surgeons. In the present study, we combined HMGB1 gelatin sponges with MSC sheets to promote bone healing after surgical treatment of rat tibial fractures. The HMGB1 gelatin sponge scaffolds supported the expansion of mes...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Xue, Deting, Zhang, Wei, Chen, Erman, Gao, Xiang, Liu, Ling, Ye, Chenyi, Tan, Yanbin, Pan, Zhijun, Li, Hang
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522052/
https://ncbi.nlm.nih.gov/pubmed/28431400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16887
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