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Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme.

Ribozymes are potentially very powerful agents for perturbing intracellular gene expression. However, pilot experiments in eukaryotes have met with mixed success. We now report that a ribozyme designed to cleave the integrase gene of the human immunodeficiency virus (HIV), when transcribed from a pl...

詳細記述

保存先:
書誌詳細
主要な著者: Sioud, M, Drlica, K
フォーマット: Artigo
言語:Inglês
出版事項: 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC52283/
https://ncbi.nlm.nih.gov/pubmed/1871136
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