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Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme.

Ribozymes are potentially very powerful agents for perturbing intracellular gene expression. However, pilot experiments in eukaryotes have met with mixed success. We now report that a ribozyme designed to cleave the integrase gene of the human immunodeficiency virus (HIV), when transcribed from a pl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sioud, M, Drlica, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52283/
https://ncbi.nlm.nih.gov/pubmed/1871136
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